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New release on opnMe.com - Access the first allosteric STEP activator for free to advance your research

19 Sept 2018

"A small step for us, but a big step to the research community"

We are happy to announce that we have added the first small molecule STEP (PTPN5) activator, BI-0314, that binds to the phosphatase domain and upregulates the catalytic activity of STEP to our opnMe.com portal.

My mission: Science - use knowledge more effectively and share earlier

04 June 2018

New ideas for molecules? He initiated the opnMe.com crowdsourcing platform - and received great reception. In a short period of time, hundreds of molecule orders and many new ideas for scientific research collaboration projects were received. #ResearchOnStage @BoehringerDE

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New molecule on opnMe.com – Start your in vitro research with our newly added, well-characterized ALK5 (TGFßR1) inhibitor

04 June 2018

As of today, Boehringer Ingelheim offers you another well-characterized and potent inhibitor via opnMe.com: BI-4659 inhibits Alk5 which is also known as TGFβR1. Therapeutic approaches to inhibit TGFβ receptor I (TGFβRI/Alk5) signaling have been discussed for the treatment of several diseases such as idiopathic pulmonary fibrosis and cancer.

Will you be the researcher who unlocks the potential of our Complex I ROS modulator?

17 May 2018

As an expert in your field, you may be excited to learn that Boehringer Ingelheim is now seeking novel disease hypotheses for its Complex I ROS modulators.

opnMe BI Miner: Connect the dots with our new co-occurrences feature - Part 3/3

08 May 2018

Have you ever wondered what the connection is between two search items? With our BI Miner co-occurrence function, you have now a tool at hand on opnMe.com to answer your questions. All for free – no costs associated. For example, if you are interested in the role of BCL6 in cancer, type “BCL6” and “Cancer” into the search fields and select your source.

opnMe BI Miner: Now also search by structures! - Part 2/3

26 April 2018

Are you ready to take the next step with BI Miner on opnMe.com? An innovative search function allows you to search for compounds based on chemical structure.

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Christian Tidona

20 April 2018

Great move of @Boehringer to provide open access to its powerful search tool BI Miner

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Have a look yourself and start to benefit today.

opnMe BI Miner: Access to save time & effort for pharmacological research queries - Part 1/3

20 April 2018

We have now launched an updated and greatly expanded version of BI Miner on opnMe. Its mission is to save time and effort when performing online scientific queries as it combines several search modes into one single tool. The search engine works very intuitively and is pretty much self-explainable.

New release on opnMe.com - Access our β2AR agonist BI-167107 for free to advance your structural research experiments

12 April 2018

Our β2 adrenergic receptor (β2AR ) agonist BI-167107 was used to support crystallization of active state β2AR and β2AR-G-protein complexes by Prof. Brian K. Kobilka as highlighted in his Nobel Prize Lecture in 2012 (The Structural Basis of G-Protein-Coupled Receptor Signaling (2012 Nobel Prize for Chemistry)). The compound could potentially be employed for the crystallization of other beta receptors.

New release on opnMe.com - Access our BRD9 and BRD7/BRD9 inhibitors for free to advance your research

19 March 2018

Boehringer Ingelheim’s well-characterized, potent and selective BRD9 inhibitor BI-9564 and the dual BRD7/BRD9 inhibitor BI-7273 are now available on opnMe.com. Both were developed in collaboration with the Structural Genomics Consortium (SGC).