Publications

General literature

DOI

Boehringer Ingelheim experiments with open-access chemical probes

A. Mullard Boehringer Ingelheim experiments with open-access chemical probes, Nature Reviews Drug Discovery 2018, 17, 7.

Molecule specific literature

DOI
PUBMED

STEP activator | BI-0314

The tyrosine phosphatase STEP: implications in schizophrenia and the molecular mechanism underlying antipsychotic medications

NC Carty, J Xu, P Kurup, J Brouillette, SM Goebel-Goody, DR Austin, P Yuan, G Chen, PR Correa, V Haroutunian, C Pittenger and PJ Lombroso

Transl Psychiatry 2012, 2, e137.

DOI
PUBMED

STEP activator | BI-0314

STEP61 is a substrate of the E3 ligase parkin and is upregulated in Parkinson’s disease

Pradeep K. Kurup, Jian Xu, Rita Alexandra Videira, Chimezie Ononenyi, Graça Baltazar, Paul J. Lombroso, and Angus C. Nairn

Proceedings of the National Academy of Sciences 2015, 112, 1202-1207.

DOI
PUBMED

STEP activator | BI-0314

Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer’s disease mouse model

Yongfang Zhang, Pradeep Kurup, Jian Xu, Nikisha Carty, Stephanie M. Fernandez, Haakon B. Nygaard, Christopher Pittenger, Paul Greengard, Stephen M. Strittmatter, Angus C. Nairn, and Paul J. Lombroso

Proceedings of the National Academy of Sciences 2010, 107, 19014-19019.