Molecules for collaboration FAQs
- Privileged access to highly characterized and cutting-edge pharmacology molecules
- Direct support from experienced Boehringer Ingelheim drug discovery scientists
- Initial enabling funding might be available with the potential for follow-on collaborations
- Possibility of publishing novel connections of biological mechanisms to human disease using unique reagents
We release these compounds for specific projects to test novel therapeutic hypotheses. The proposals are evaluated by Boehringer Ingelheim scientists and the selected ideas are normally pursued through a joint collaboration. Initial proposals should be short and address the following areas to allow rapid evaluation of your ideas. The submitted proposal must not contain any confidential data.
- Overview of the proposal originator and the organization(s) it represents
- Medical need
- Scientific rationale [supported by key references]
- Target-to-disease link
- Therapeutic hypothesis to be tested
- Test systems available and information on their suitability
- Key decision-making data to support project progression
- Projected timelines to decision points
A graphical representation of the experimental plan - Information on potential conflicting intellectual property rights of third parties and freedom to operate
- Initial funding request
A template provided by us will help you to compile the information required.
If confidential data exists that would strengthen the proposal, you may indicate that confidential information is available to share under a Confidential Disclosure Agreement (CDA). If we find the non‐confidential concept proposal sufficiently interesting, we will execute a CDA for confidential discussions.
Funding is potentially available to kick-start projects. Research proposals are evaluated by Boehringer Ingelheim scientists for strategic fit and are considered for funding on a competitive basis.
Boehringer Ingelheim scientists with relevant expertise will make an initial evaluation of your collaboration proposal within 4 weeks. Should there be mutual interest in proceeding with the compound request, you will usually be contacted by a Boehringer Ingelheim scientist to discuss the research plan in more detail and to understand how we can best support your idea. The timeframe for collaboration start will be different for each collaboration.
Yes, all molecules that can be ordered on opnMe.com (Molecules to order) will be shipped free of charge. This means we cover the costs of synthesis and shipping up to your bench. For shipments outside of Europe, we have to provide a pro-forma value for our molecules to meet international customs regulations. The value of 2,16 €/mg is declared for customs purpose only. Please note that local custom fees may apply and we advise you to check with your local authorities. In case of questions, please contact us for further information.
Sufficient compound will be provided to test the new therapeutic concept as outlined in the agreed research plan.
The IP rights will be pre-negotiated as part of the contracting arrangements between Boehringer Ingelheim and your institution.
These molecules are also released with a comprehensive data package describing potency on designated target, selectivity information versus other targets and pharmacokinetic characterization. In the first instance, these structures are not released. This allows us to make unique compounds from ongoing projects available to the community much earlier than has previously been possible.
These tool compounds highly characterized with respect to potency, selectivity and pharmacokinetics. They are suitable for in vivo preclinical studies and guidelines are available to advise on species previously tested, dose selection, dose regimen, and formulation.
No. We aim to make unique tool compounds available at a very early stage as the biology is evolving; hence, the compounds will not have been subject to a comprehensive safety evaluation. They are provided as experimental tools for in vitro and in vivo studies and should be treated appropriately according to the practices within your institute.
If you would like to modify and re-upload your proposal, the easiest way would be to start a new submission process and submit your updated proposal that way. Please let us know of the initial proposal ID that you would like to retract, so we can delete it accordingly from our system and only consider your updated proposal for the evaluation process.